How is the brittleness of Pharmaceutical hard gelatin empty capsule?

The brittleness of pharmaceutical hard gelatin empty capsules is a relatively complex issue, as it is influenced by multiple factors.
Firstly, the brittleness of pharmaceutical hard gelatin empty capsules is closely related to their preparation process. If there are improper controls on temperature, humidity, pressure, etc. during the preparation process, it may affect the quality and stability of the capsule, leading to an increase in its brittleness.
Secondly, the brittleness of pharmaceutical hard gelatin empty capsules is also related to their composition. For example, factors such as the moisture content in the capsule, the molecular weight of gelatin, and crosslinking degree may all affect the brittleness of the capsule. If these factors are not properly controlled, it may lead to capsules becoming fragile and fragile.
In addition, pharmaceutical hard gelatin empty capsules may also be affected by some environmental factors during storage and use, such as temperature, humidity, light, etc. If stored improperly, it may lead to aging and increased brittleness of the capsules.
However, it should be pointed out that pharmaceutical hard gelatin hollow capsules produced by legitimate manufacturers usually undergo strict quality control and stability testing to ensure their safety and effectiveness during use. Therefore, under normal circumstances, the brittleness of pharmaceutical hard gelatin empty capsules should be relatively low.
Overall, the brittleness of pharmaceutical hard gelatin empty capsules is a relatively complex issue that is influenced by multiple factors. However, through strict preparation processes, quality control, and storage condition control, the quality and stability of capsules can be ensured, thereby reducing their brittleness.