Is there any relationship between the size of pharmaceutical hard gelatin empty capsule and the dosage requirement of the product?

Yes, the size of pharmaceutical hard gelatin empty capsule is closely related to the dosage requirements of the product. The size of the capsule determines the amount of medication it can hold inside, so it is necessary to choose the appropriate size of the capsule according to the dosage requirements of the product.
Usually, the size of pharmaceutical hard gelatin empty capsule is represented by numbers, ranging from 000 to 5, with smaller numbers indicating smaller capsules. Capsules of different sizes have different internal volumes, making them suitable for different doses of fillers.
Larger capsules (such as size 000 or 00) are typically used for products that require high doses, such as nutritional supplements or high-dose medications. They have a larger internal volume and can accommodate more fillers.
Medium sized capsules (such as size 0 or 1) are suitable for medium dose products, such as regular drug doses or supplements.
Smaller sized capsules (such as sizes 2 to 5) are typically used for products that require smaller doses, such as pediatric medications or certain herbal formulas.
Therefore, selecting the appropriate size of pharmaceutical hard gelatin empty capsule is crucial to ensure the accuracy and suitability of the product dosage. When choosing a capsule size, factors such as the dosage form, ingredient content, target audience, and manufacturing process limitations of the product need to be considered. It is usually recommended to carefully calculate and test the dosage before formula development and production to ensure that the selected capsule size meets the dosage requirements of the product.